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LMNA cardiac / LMNA related cardiac diseases network

LMNA cardiac / LMNA related cardiac diseases network

LMNA related cardiac diseases information and network

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Introduction

Introduction to LMNA related DCM

Dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a clinical diagnosis characterized by left ventricular or biventricular dilation, and impaired contraction of the heart (see Figure 1), that is not caused by abnormal loading conditions as hypertension, valvular heart disease, or coronary artery disease1.

DCM can originate from a  wide variety of conditions , such as viral/bacterial infections, underlying auto-immune diseases, metabolic disorders, neuromuscular disorders or genetic mutations1. Mutations in several genes can cause DCM, including genes encoding structural components of the cell nucleus, such as the LMNA gene, encoding for the proteins Lamin A and Lamin C, being components of the nuclear lamina.Dilated cardiomyopathy

We have more information and data relating to DCM that we would be happy to share with you, and/or connect you to others in our network where possible.

Coming soon to LMNAcardiac.org:

  • Disease insights
  • R&D Opportunities
  • Key Opinion Leaders (KOL) and companies active in the field

Source: Catalyze Group (LMNAcardiac.org worked together with Catalyze group for research into this field)

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DCM Foundation - LMNA webinar

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