We are proud to share that LMNA Cardiac Diseases Network (LMNAcardiac.org) has been affiliated with several recent scientific publications focused on LMNA-related cardiomyopathy and laminopathies. These collaborations reflect the growing importance of patient organizations in accelerating research, increasing awareness, and supporting the development of future therapies.
Among the recent publications:
- “From gene to mechanics: a comprehensive insight into the mechanobiology of LMNA mutations in cardiomyopathy” explores how LMNA mutations affect the heart at the molecular and mechanical level, providing important insights into disease mechanisms and potential therapeutic targets.
https://pubmed.ncbi.nlm.nih.gov/38539233/ - “Setting the stage for cardiomyopathy gene editing trials” discusses progress toward gene-editing approaches for inherited cardiomyopathies, including advanced cellular models that may help prepare future clinical trials.
https://pubmed.ncbi.nlm.nih.gov/41536960/ - “Metabolic Dysregulation in Laminopathies: Implications for Disease Pathogenesis and Therapeutic Approaches” highlights emerging evidence linking LMNA mutations and laminopathies to metabolic dysfunction and discusses potential therapeutic opportunities.
https://pubmed.ncbi.nlm.nih.gov/41627535/
At LMNAcardiac.org, we believe strong collaboration between researchers, clinicians, patients, and families is essential to move the field forward. We are grateful to all scientists and partners who continue to work toward better treatments and ultimately a cure for LMNA-related cardiac disease.
We will continue updating this page as new research publications and collaborations become available.